Download or read book Molecular Characterization and Functional Analysis of a Novel Long Noncoding RNA in the Mouse written by Parth Devesh Joshi and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Majority of mammalian transcriptomes encode long noncoding RNAs (lncRNAs) that are not translated into proteins. LncRNAs are mRNA-like transcripts that are longer than 200 nucleotides, transcribed by RNA-Pol-II and undergo post-transcriptional modifications and splicing. Although they are less evolutionary conserved than protein-coding genes, lncRNAs have been shown to regulate several biochemical and cellular processes at a transcriptional level. Yet to date, the mechanism of only a handful of them has been studied in mammalian organisms. Therefore, in order to understand the function of l...