Download or read book Cross-modulatory Actions of Estrogen Receptor Beta on Estrogen Receptor Alpha Transcriptional Activity in Breast Cancer Cells written by Edmund Chi-Ru Chang and published by ProQuest. This book was released on 2007 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our observations indicate that the ability of ERalpha and ERbeta to serve as determinants of gene expression is greatly influenced by the nature of the ligand, ligand dose, and the ability of ligand-ER complexes to recruit coregulators at ER binding sites of hormone-regulated genes.