The Discovery of New Medicines in Academia

The Discovery of New Medicines in Academia
Author :
Publisher : Elsevier
Total Pages : 306
Release :
ISBN-10 : 9780443293252
ISBN-13 : 0443293252
Rating : 4/5 (52 Downloads)

Book Synopsis The Discovery of New Medicines in Academia by :

Download or read book The Discovery of New Medicines in Academia written by and published by Elsevier. This book was released on 2024-07-24 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Discovery of New Medicines in Academia, Volume 100 highlight examples of discoveries originating in academia that have been successfully translated into promising therapeutics that have advanced into clinical trials. Chapters in this release cover Design and Discovery of Itaconate prodrugs for Alopecia Areata, Hydroxyl-Dendrimer Delivery System for Neurological Disease, Development of allosteric modulators of G protein-coupled receptors for Psychiatric Disease, Targeting the constitutively active ERK1/2 signaling kinase for cancer, mRNA reprogramming of myeloid cells for tumor immunotherapy, Development of novel drugs targeting protein-protein interactions, and much more.Additional sections cover Neuro-steroids and analogs for the treatment of epilepsy, Development of inhibitors of eukaryotic translation, Discovery/development of antiviral, anticancer and/or anti-inflammatory agents, Discovery of novel anti-infective agents, Targeting proliferating cell nuclear antigen (PCNA) for cancer, and Implementation and Evolution of Quantitative Systems Pharmacology to Patient Digital Twins and Biomimetic Twins. - Provides recent examples of successful academic drug discovery projects in multiple disease areas, including oncology, immunology, neurology, and infectious diseases - Presents diverse examples, including small molecule, biologic, and nanomedicine-based therapeutics - Discusses innovative artificial intelligence platforms utilized in academic drug discovery efforts


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