Download or read book Post-Polymerization Modification of Block Copolymers for Functionalization-Induced Self-Assembly written by David H. Howe and published by . This book was released on 2020 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis is focused on expanding the utility of post-polymerization modification (PPM) and establishing it as a viable route for the synthesis of self-assembled polymeric nanoparticles through three primary research projects. The first project demonstrates Pd-catalyzed, Suzuki-Miyaura cross-coupling (SMC) as a new, versatile method for PPM on well-defined polymers derived from RAFT polymerization. The second project aims to employ SMC as the driving force behind a novel strategy for inducing dynamic self-assembly of block copolymers into nanoparticles through a technique termed "functionalization induced self-assembly" (FISA). The final project of this thesis improves upon the versatility and ease-of-use of FISA by extending it to the base-catalyzed thiol-epoxide "click" reaction as the primary PPM driving in situ self-assembly, thus achieving convenient polymer nanoparticle synthesis under ambient conditions and atmosphere. Keywords: click reaction, nanoparticle, polymer, RAFT, self-assembly, Suzuki