High Throughput Bioanalytical Sample Preparation

High Throughput Bioanalytical Sample Preparation
Author :
Publisher :
Total Pages : 648
Release :
ISBN-10 : UOM:39015056471918
ISBN-13 :
Rating : 4/5 (18 Downloads)

Book Synopsis High Throughput Bioanalytical Sample Preparation by : David A. Wells

Download or read book High Throughput Bioanalytical Sample Preparation written by David A. Wells and published by . This book was released on 2003-01-28 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: High Throughput Bioanalytical Sample Preparation: Methods and Automation Strategies is an authoritative reference on the current state-of-the-art in sample preparation techniques for bioanalysis. This book focuses on high throughput (rapid productivity) techniques and describes exactly how to perform and automate these methodologies, including useful strategies for method development and optimization. A thorough review of the literature is included within each of these chapters describing high throughput sample preparation techniques: protein removal by precipitation; equilibrium dialysis and ultrafiltration; liquid-liquid extraction; solid-phase extraction; and various on-line techniques. The text begins with an introductory overview of the role of bioanalysis in pharmaceutical drug development. Fundamental understanding of the strategies for sample preparation is reinforced next, along with essential concepts in extraction chemistry. Several chapters introduce and discuss microplates, accessory products and automation devices. Particular strategies for efficient use of automation within a bioanalytical laboratory are also presented. The subject material then reviews protein precipitation, liquid-liquid extraction, solid-phase extraction and various on-line sample preparation approaches. The book concludes with information on recent advances in sample preparation, such as solid-phase extraction in a card format and higher density extraction plates. Important objectives that can be accomplished when the strategies presented in this book are followed include: improved efficiency in moving discovery compounds to preclinical status with robust analytical methods; return on investment in automation for sample preparation; and improved knowledge and expertise of laboratory staff. · Shows the reader exactly how to perform modern bioanalytical sample preparation techniques, complete with detailed strategies · Thorough literature review and summary of published information · Detailed discussion and examples of the method development process


High Throughput Bioanalytical Sample Preparation Related Books

High Throughput Bioanalytical Sample Preparation
Language: en
Pages: 648
Authors: David A. Wells
Categories: Medical
Type: BOOK - Published: 2003-01-28 - Publisher:

DOWNLOAD EBOOK

High Throughput Bioanalytical Sample Preparation: Methods and Automation Strategies is an authoritative reference on the current state-of-the-art in sample prep
Sample Preparation in LC-MS Bioanalysis
Language: en
Pages: 384
Authors: Wenkui Li
Categories: Science
Type: BOOK - Published: 2019-03-12 - Publisher: John Wiley & Sons

DOWNLOAD EBOOK

Revised and Expanded Handbook Provides Comprehensive Introduction and Complete Instruction for Sample Preparation in Vital Category of Bioanalysis Following in
Sample Preparation for Hyphenated Analytical Techniques
Language: en
Pages: 237
Authors: Jack Rosenfeld
Categories: Science
Type: BOOK - Published: 2009-02-12 - Publisher: John Wiley & Sons

DOWNLOAD EBOOK

Linking “standard” but often mutually incompatible analytical techniques – so called hyphenation – generally leads to enhanced analytical performance, s
Sample Preparation in LC-MS Bioanalysis
Language: en
Pages: 784
Authors: Wenkui Li
Categories: Science
Type: BOOK - Published: 2019-02-25 - Publisher: John Wiley & Sons

DOWNLOAD EBOOK

Revised and Expanded Handbook Provides Comprehensive Introduction and Complete Instruction for Sample Preparation in Vital Category of Bioanalysis Following in
Handbook of Solid Phase Microextraction
Language: en
Pages: 497
Authors: Janusz Pawliszyn
Categories: Science
Type: BOOK - Published: 2011-12-01 - Publisher: Elsevier

DOWNLOAD EBOOK

The relatively new technique of solid phase microextraction (SPME) is an important tool to prepare samples both in the lab and on-site. SPME is a "green" techno