Ligand Design for G Protein-coupled Receptors

Ligand Design for G Protein-coupled Receptors
Author :
Publisher : John Wiley & Sons
Total Pages : 284
Release :
ISBN-10 : 9783527608263
ISBN-13 : 3527608265
Rating : 4/5 (63 Downloads)

Book Synopsis Ligand Design for G Protein-coupled Receptors by : Didier Rognan

Download or read book Ligand Design for G Protein-coupled Receptors written by Didier Rognan and published by John Wiley & Sons. This book was released on 2006-08-21 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: G protein-coupled receptors (GPCRs) are one of the most important target classes in pharmacology and are the target of many blockbuster drugs. Yet only with the recent elucidation of the rhodopsin structure have these receptors become amenable to a rational drug design. Based on recent examples from academia and the pharmaceutical industry, this book demonstrates how to apply the whole range of bioinformatics, chemoinformatics and molecular modeling tools to the rational design of novel drugs targeting GPCRs. Essential reading for medicinal chemists and drug designers working with this largest class of drug targets in the human genome.


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