Validation of Alternative Methods for Toxicity Testing

Validation of Alternative Methods for Toxicity Testing
Author :
Publisher : Springer
Total Pages : 418
Release :
ISBN-10 : 9783319338262
ISBN-13 : 3319338269
Rating : 4/5 (62 Downloads)

Book Synopsis Validation of Alternative Methods for Toxicity Testing by : Chantra Eskes

Download or read book Validation of Alternative Methods for Toxicity Testing written by Chantra Eskes and published by Springer. This book was released on 2016-09-26 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and transcriptomics, and for methods derived from pathway-based concepts in toxicology. Validation of Alternative Methods for Toxicity Testing is divided into two sections, in the first, practical insights are given on the state-of-the-art and on approaches that have resulted in successfully validated and accepted alternative methods. The second section focuses on the evolution of validation principles and practice that are necessary to ensure fit-for-purpose validation that has the greatest impact on international regulatory acceptance of alternative methods. In this context validation needs to keep pace with the considerable scientific advancements being made in toxicology, the availability of sophisticated tools and techniques that can be applied in a variety of ways, and the increasing societal and regulatory demands for better safety assessment. This book will be a useful resource for scientists in the field of toxicology, both from industry and academia, developing new test methods, strategies or techniques, as well as Governmental and regulatory authorities interested in understanding the principles and practicalities of validation of alternative methods for toxicity testing.


Validation of Alternative Methods for Toxicity Testing Related Books

Validation of Alternative Methods for Toxicity Testing
Language: en
Pages: 418
Authors: Chantra Eskes
Categories: Medical
Type: BOOK - Published: 2016-09-26 - Publisher: Springer

DOWNLOAD EBOOK

This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation
Validation of Alternative Methods. Toxicity Testing Without Animals
Language: en
Pages:
Authors:
Categories:
Type: BOOK - Published: 2003 - Publisher:

DOWNLOAD EBOOK

Alternatives To Animal Testing
Language: en
Pages: 137
Authors: R E Hester
Categories: Science
Type: BOOK - Published: 2007-10-31 - Publisher: Royal Society of Chemistry

DOWNLOAD EBOOK

Animal experimentation has long been a controversial issue with impassioned arguments on both sides of the debate. Increasingly it has become more expedient and
Alternative Methods for Toxicity Testing
Language: en
Pages: 192
Authors:
Categories: Animal experimentation
Type: BOOK - Published: 1986 - Publisher:

DOWNLOAD EBOOK

Validation and Regulatory Acceptance of Toxicological Test Methods
Language: en
Pages: 95
Authors: DIANE Publishing Company
Categories:
Type: BOOK - Published: 1998-02 - Publisher: DIANE Publishing

DOWNLOAD EBOOK